Donato J. Tramuto Joins Physicians Interactive

27-Year Healthcare Veteran and Former CEO of i3 Named President of Allscripts Physician Interactive Business Group

CHICAGO (November 16, 2006) –

Allscripts (Nasdaq: MDRX), the leading provider of clinical software, connectivity and information solutions that physicians use to improve healthcare, announced today that Donato J. Tramuto has joined the Company as President of the Physicians Interactive(TM) (PI) business group. Mr. Tramuto will lead the strategic expansion of the Physicians Interactive business model into new markets within the pharmaceutical and managed healthcare marketplace and accelerate the introduction of a number of new products and services scheduled to be released over the next six months.

(Logo: http://www.newscom.com/cgi-bin/prnh/20061005/ALLSCRIPTSLOGO-b )

“Donato’s experience, market knowledge, and executive level business relationships within the pharmaceutical and managed care industries will help Physicians Interactive capitalize on new revenue opportunities,” said Glen Tullman, Chief Executive Officer of Allscripts. “Donato is a world-class executive with a strong operating background and a track record of driving results. He will help Allscripts deliver an expanded value proposition to our major stakeholders and become a member of our senior leadership team.” Mr. Tramuto has more than 27 years of healthcare experience in both the product and service segments. He was previously Chief Executive Officer of i3, a global pharmaceutical services company that is part of Ingenix (a UnitedHealth Group Company), overseeing the Clinical Research, Pharmaceutical Data, Analytics, Outcomes, EPI/Safety, Health Education, and Strategic Consulting business units.

Prior to joining Ingenix, Mr. Tramuto was one of the founders of Protocare, Inc., a large provider of drug development services, where he served as Chief Executive and President of the Protocare Sciences Division and Corporate Officer of Protocare from 1998 to 2003. Prior to co-founding Protocare, Mr. Tramuto was Corporate Vice President of Marketing/Healthcare at Caremark, where he helped create the company’s first disease management program for HIV/AIDS.

Mr. Tramuto is the Chairman and founder of the Donato J. Tramuto Foundation, a non-profit organization that he founded in 2001 to help disadvantaged youth reach their educational goals. He also serves on the Duke University Fuqua Health Care Advisory Board. In August of 2005, Mr. Tramuto was selected by PharmaVoice as one of the “Top 100 Most Inspirational Healthcare Leaders In the Life Sciences Industry.”

“I am committed to the idea that advanced technology, when coupled with real-time data, provides a unique opportunity to create information products that help physicians, pharmaceutical organizations, and managed care organizations,” said Mr. Tramuto. “I believe that Allscripts is poised to deliver on this unique combination and I look forward to helping the company build on that strong position.”

About Physicians Interactive

Physicians Interactive (PI) is the market leader in innovative and interactive product solutions for physicians and healthcare professionals. PI builds strong relationships with physicians by utilizing Internet-based, interactive programs to deliver valuable, up-to-date clinical information about medical products, both at the point of care and outside the practice setting. PI is a trusted physician communication platform, servicing 46 pharmaceutical, biotech, and medical device companies, including nine of the top 10 major pharmaceutical firms. PI operates in nine countries and the United States, and is uniquely positioned to capture a growing share of the physician information and education marketplace. Physicians Interactive is a division of Allscripts.

About Allscripts

Allscripts is the leading provider of clinical software, connectivity and information solutions that physicians use to improve healthcare. The Company’s business groups provide unique solutions that inform, connect and transform healthcare. The Clinical Solutions Group’s award-winning software applications include electronic health record, practice management, electronic prescribing, document imaging, emergency department and care management solutions. Additionally, Allscripts provides clinical product education and connectivity solutions for physicians and patients through its Physicians Interactive(TM) Group and medication fulfillment services through its Medication Services Group. To learn more, visit Allscripts on the Web at http://www.allscripts.com .

This announcement may contain forward-looking statements about Allscripts Healthcare Solutions that involve risks and uncertainties. These statements are developed by combining currently available information with Allscripts beliefs and assumptions. Forward-looking statements do not guarantee future performance. Because Allscripts cannot predict all of the risks and uncertainties that may affect it, or control the ones it does predict, Allscripts’ actual results may be materially different from the results expressed in its forward-looking statements. For a more complete discussion of the risks, uncertainties and assumptions that may affect Allscripts, see the Company’s 2005 Annual Report on Form 10-K, available through the Web site maintained by the Securities and Exchange Commission at http://www.sec.gov .

SOURCE Allscripts
-0- 11/16/2006
/CONTACT: Dan Michelson, Chief Marketing Officer, +1-312-506-1217
dan.michelson@allscripts.com , Todd Stein, Public Relations Director,
+1-312-506-1216, todd.stein@allscripts.com , both of Allscripts, or, Matthew
Bloom, Marketing Director of Physicians Interactive, +1-847-680-3515,
matthew.bloom@allscripts.com /
/Photo: http://www.newscom.com/cgi-bin/prnh/20061005/ALLSCRIPTSLOGO-b
AP Archive: http://photoarchive.ap.org
PRN Photo Desk, photodesk@prnewswire.com /
/Web site: http://www.allscripts.com/
(MDRX)

CO: Allscripts
ST: Illinois
IN: HEA MTC CPR STW
SU: PER

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3130 11/16/2006 09:41 EST http://www.prnewswire.com

Source: Allscripts